Dr. Maigaelle Moulene Long Covid
Resource

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​​​ TREATMENT PROTOCOLS:

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Dr. Moulene's Long Covid Healing Support:

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Here is the Treatment Protocol I have devised for myself that I am currently on and is helping with my symptoms: 

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- Symprove probiotic 75ml / Inulin 5g first thing in the morning 

 

Morning: 

1. Duloxetine 30mg in the morning

2. NAC 600mg 

3. CoQ10 300mg

4. Omega 3: EPA 660mg/DHA 440mg

5. Vitamin C 100-500mg 

6. Vitamin D 2,000 units 

7. Vitamin B12 2,000 mcg /Folate 200mcg 

8. Zinc 22mg

9. Alpha Lipoic Acid up to 3x300mg 

10. L-Arginine 500mg

11. Gingko Biloba 240 mg

12. Turmeric (Curcumin) 2,600mg (49.1mg) & Ginger 500mg

13. Inositol Choline 250mg/250mg

14. Probiotics 30 Billion: depending on bacterial deficiencies. 

​15. Vitamin B6 100mg

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Meditation/Red light therapy/stretching

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Slippery Elm Tea: 5mg slippery elm powder, sweetener, boiling water, almond milk

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Lunch:

1. Probiotics

2. Cranberry capsules

3. Caprylic Acid

4. Butyric Acid 

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Evening: L-Glutamine 

1. Cetirizine 10-15mg

2. Ketotifen 1-2 mg

3. Magnesium Glycinate 500mg

4. 3 -10 mg Melatonin

5. Phosphatidyl Serine 200mg

6. Apigenin

7. Ashwagandha/hemp tea 

8. CBD Balm

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CBD oil as needed

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Treatments based on the Cause of Long Covid: 

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All Long Covid patients should be on a general inflammation protocol and be treated for low serotonin and most will likely need treatment for Mast Cell Activation Syndrome and POTS if they have been diagnosed. Try the below protocols at your own risk. Check any drug interactions prior to trialling these medications and supplements. 

Take a stepwise approach, starting with the first treatment option for one week, and continue if tolerated. If symptoms are not sufficiently controlled, add the next treatment option. 

*Starred treatment are ones that helped me the most..*

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General Inflammation Treatment: all are anti - inflammatory

1. *NAC 600 - 1200mg / day (8)

2. Turmeric Up to 8g/ day (9)

3. Omega 3 0.5g / day (10) 

4. Gingko Biloba (11)

5. Zinc (12) 

6, Vitamin C (13)

7. L - Arginine (13) 

8.  Tea: Apigenin = Green tea , Nettle tea, ginger tea, Marshmallow root tea, cinnamon (16)

9 . CBD (14)

9. Propolis (15) 

10. Ginger (17)

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DRUG TREATMENT FOR INFLAMMATION:

- LDN: General Inflammation

- Nicotine Patches: General Inflammation 

- Pregabalin: Neuropathic Pain 

- THC/CBD: pain, MCAS treatment, inflammation

- SSRIs: To increase Serotonin levels. ​​ 

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MAST CELL ACTIVATION SYNDROME Treatment:

Dr.  Monroy a MCAS specialist based in the US wrote an excellent protocol for MCAS Management: (7)

MCAS DIET:

- Exclude gluten/dairy/histamine food

- Avoid triggers (stress, mould, electricity, chemical triggers, hair colouring etc...)

- Good food: apples, brazil nuts, chamomile, high fiber diet, galangal, moringa, nettle tea, peaches, turmeric, Vitamin C and D. 

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- MCAS Step 1 Therapy:

Add one at a time every 4 days to test tolerance. 

1. H2 Blockers: Pepcid of Famotidine. Start 20mg twice and day and increase to 20mg three times a day. Or Nizatadine. 

2. H1 Blockers: Claritin 10mg or *Zyrtec (Cetirizine) 10mg twice a day or Allegra 180mg one to two times a day. 

3. Quercetin: 500-1000 mg twice a day

4. Vitamin C slow release: 500mg once a day up to 750/1000mg a day

5. Vitamin D 1000-5000 units per day (depending on blood levels).

6. Low Dose Naltrexone: to reduce inflammatory proteins which can trigger MCAS. Start at 1mg and gradually increase up to 4.5mg

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If tolerating the above yet symptoms not controlled, to try substitutes for LDN/Quercetin: 

7. Cromolyn- start at 1 ampule per week, slowly increase to 2 ampules four times a day over a few weeks.

8. *Ketotifen: 2mg (one - two capules) 1-2 times per day. 

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MCAS Step 2 Therapy

Low doses aspirin: start 81mg and increase to 650mg twice a day. 

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MCAS Step 3 Therapy

Immune Globulin Therapy: useful if co-morbid auto-immune POTS.

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Natural Therapies for MCAS:

1. Dynamic neural retraining system: http: www.retrainingthebrain.com

2. Vagus Nerve retraining

3. Gut health: Probiotics Lactobacillus Rhamonosus, Bifidobacter species. 

4. Gut health: Zinc, Carnosine, L-Glutamine with meals 2 times a day. 

5. DAO enzymes with meals. 

6. Alpha Lipoic Acid 600mg 

7. Omega 3 Fatty Acids

8. N-Acetyl-Cisteine

9. Mitochondrial Support: L Carnitine 2000mg twice a day and CoQ10 200mg twice a day. 

10. CBD Oil: ie. Hemp Meds, CBD Fx

11. THC: there are THC and CBD receptors on mast cells and can reduce inflammation. 

12. Adrenal Support: DHEA, Rhodiola, Ashwagandha helps sleep and may help decrease histamine hi

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Gut Inflammation (Abdominal Pain/Bloating/Reflux) 

1. L-Glutamine to treat leaky gut​ (19)

2. Symprove Probiotics (20)

3. Proton pump inhibitors for reflux (22)

4. Probiotics for pain/bloating (20)

5. Butyric Acid to heal the gut (21)

6. Slippery Elm for reflux (22)

7. Aloe Vera juice for reflux and LC treament (23)

8. Fennel Tea/Marshmallow root/chamomile (22)

9. Inulin post biotics (20)

10. Collagen 

11. Creatinine

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Immune Dysfunction (Increased Infections)

1. Vitamin C (13)

2. Zinc (12)

3. Vitamin D

4. Prevent infections: D-Mannose/Cranberry for UTI, Caprylic Acid for thrush/candida. 

5. Treat Infections

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Autonomic Dysfunction/POTS (Tachycardia/Fatigue/Hyperadrenaline)

1. Beta Blockers: Metoprolol or Propanolol

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Circulatory System Damage & Clotting (Breathlessness/Brain Fog)

1. Aspirin OR Gingko Biloba OR Nattokinase (dissolves blood clots)

2. L- Arginine for Endothelial dysfunction (

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Nerve Damage/Inflammation/Peripheral Neuropathy (Neuropathic Pain Treatment)

1. NAC (8)

2. * CBD

3. Turmeric (9)

4. Quercetin (if tolerated)

5. Gingko Biloba

6. Sage/Rosemary

7, SNRIs: Pregabalin/Gabapentin/Amitryptiline

8. High dose Vitamin B

9. Acupuncture

10. Lidocaine pathch/gel

11. GABA: 100-300mg

12. Anti-histamine

13 Berberine

14. Inositol Choline

15. N - Acetyl - Carnitine

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Brain Inflammation (Brain Fog)

1. *NAC

2. Alpha Lipoic Acid

3. Inositol Choline

4. Duloxetine

5. B12

6. Phosphatidyl Choline

7. Omega 3

8. Gingko Biloba

9. Turmeric 

10. Vagus Nerve treatment 

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Decreased Serotonin (Shortness of Breath/Brain Fog/Fatigue/Low Mood)

1. *SSRIs: Duloxetine​​

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Mitochondrial Dysfunction/Damage (Fatigue/PEM/Shortness of Breath/Low Energy)

1. CoQ10

2. NAC

3. Gingko Biloba

4. NMN

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Brain Fog/Cognitive Dysfunction/Neuroinflammation: Treat Brain Inflammation and increase oxygen to the brain.

1. Hyperbaric Oxygen Therapy (as needed)

2. As per MCAS Treatment: Nasal Cromolyn, Braingain: algonot.com/braingain, Neuroprotek, retrainingthebrain.com

3. Brain Inflammation treatment

4. Treat POTS: Inadequate blood flow to brain with poor oxygen delivery​

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Persistent Viral Reservoir

Nattokinase 

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Hormonal Problems 

1. HRT ​

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